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Gene: Atp4a (ATPase H+/K+ transporting subunit alpha) Rattus norvegicus
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Symbol: Atp4a
Name: ATPase H+/K+ transporting subunit alpha
Description: Predicted to have potassium:proton exchanging ATPase activity; protein heterodimerization activity; and sodium:potassium-exchanging ATPase activity. Predicted to be involved in several processes, including inorganic cation transmembrane transport; monovalent inorganic cation homeostasis; and regulation of proton transport. Localizes to the apical plasma membrane. Orthologous to human ATP4A (ATPase H+/K+ transporting subunit alpha); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; esomeprazole pharmacokinetics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATPase H+/K+ transporting alpha subunit; ATPase H+K+-transporting alpha / (gastric HK-ATPase catalytic subunit); ATPase, H+,K+-transporting, alpha / (gastric H,K-ATPase catalytic subunit); ATPase, H+/K+ exchanging, alpha polypeptide; ATPase, H+/K+ transporting, alpha polypeptide; gastric H(+)/K(+) ATPase subunit alpha; gastric H,K-ATPase catalytic subunit; H+,K+-ATPase alpha subunit; Hka; HKATPC; hydrogen/potassium-exchanging ATPase 4A; potassium-transporting ATPase alpha chain 1; proton pump; RATHKATPC
Orthologs:
Homo sapiens (human) : ATP4A (ATPase H+/K+ transporting subunit alpha)  HGNC  Alliance
Mus musculus (house mouse) : Atp4a (ATPase, H+/K+ exchanging, gastric, alpha polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp4a (ATPase H+/K+ transporting subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Canis lupus familiaris (dog) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp4a (ATPase H+/K+ transporting subunit alpha)
Sus scrofa (pig) : ATP4A (ATPase H+/K+ transporting subunit alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0189,162,700 - 89,175,504 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,162,639 - 89,175,811 (+)Ensembl
Rnor_5.0190,317,629 - 90,330,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,756,388 - 85,769,192 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.152,286,438 - 2,286,714 (+)NCBI
Celera180,333,302 - 80,346,109 (+)NCBICelera
Cytogenetic Map1q21NCBI
RH 2.0 Map1561.1RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Atp4a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2177
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.