Gene: Atp7a (ATPase copper transporting alpha) Rattus norvegicus
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Symbol: Atp7a
Name: ATPase copper transporting alpha
Description: Exhibits Rac GTPase binding activity and chaperone binding activity; involved in several processes, including cellular response to metal ion, gland development, and regulation of ion transport; localizes to several cellular components, including the apical plasma membrane, basolateral plasma membrane, and cytoplasm; biomarker of Alzheimer's disease, Wilson disease, congenital diaphragmatic hernia, and iron deficiency anemia; orthologous to human ATP7A (ATPase copper transporting alpha); PARTICIPATES IN cisplatin drug pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2,2-tetramine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATPase Cu++ transporting alpha polypeptide (Menkes syndrome); ATPase, Cu++ transporting, alpha polypeptide; ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome); copper pump 1; copper-transporting ATPase 1; menkes disease-associated protein homolog; Mnk
Orthologs:
Homo sapiens (human) : ATP7A (ATPase copper transporting alpha)  HGNC  Alliance
Mus musculus (house mouse) : Atp7a (ATPase, Cu++ transporting, alpha polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp7a (ATPase copper transporting alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP7A (ATPase copper transporting alpha)
Canis lupus familiaris (dog) : ATP7A (ATPase copper transporting alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp7a (ATPase copper transporting alpha)
Sus scrofa (pig) : ATP7A (ATPase copper transporting alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X77,076,085 - 77,193,644 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X56,198,947 - 56,313,382 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X94,192,540 - 94,249,776 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X94,265,972 - 94,323,206 (+)NCBI
CeleraX72,450,404 - 72,510,070 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Atp7a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2179
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.