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Gene: Bcan (brevican) Rattus norvegicus
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Symbol: Bcan
Name: brevican
Description: Predicted to have calcium ion binding activity; carbohydrate binding activity; and hyaluronic acid binding activity. Involved in cell-matrix adhesion; nervous system development; and regulation of neuronal synaptic plasticity. Localizes to several cellular components, including GABA-ergic synapse; main axon; and perineuronal net. Used to study malignant glioma. Biomarker of malignant glioma and middle cerebral artery infarction. Orthologous to human BCAN (brevican); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ALPBRE; BEHAB; brain-enriched hyaluronan-binding protein; Brevican (brain specific proteoglycan in the aggrecan family); brevican core protein
Orthologs:
Homo sapiens (human) : BCAN (brevican)  HGNC  Alliance
Mus musculus (house mouse) : Bcan (brevican)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcan (brevican)
Pan paniscus (bonobo/pygmy chimpanzee) : BCAN (brevican)
Canis lupus familiaris (dog) : BCAN (brevican)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcan (brevican)
Sus scrofa (pig) : BCAN (brevican)
Chlorocebus sabaeus (African green monkey) : BCAN (brevican)
Heterocephalus glaber (naked mole-rat) : Bcan (brevican)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02187,359,674 - 187,373,133 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,359,677 - 187,372,657 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02206,762,691 - 206,776,016 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,067,864 - 180,080,942 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12180,022,993 - 180,030,847 (-)NCBI
Celera2167,401,907 - 167,414,841 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Bcan
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2194
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.