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Gene: Bckdk (branched chain ketoacid dehydrogenase kinase) Rattus norvegicus
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Symbol: Bckdk
Name: branched chain ketoacid dehydrogenase kinase
Description: Exhibits ATP binding activity; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity; and protein serine/threonine kinase activity. Involved in branched-chain amino acid catabolic process and phosphorylation. Localizes to the mitochondrial alpha-ketoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in branched-chain keto acid dehydrogenase kinase deficiency. Orthologous to human BCKDK (branched chain keto acid dehydrogenase kinase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; clofibric acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; BCKD-kinase; BCKDHKIN; branched chain keto acid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase
Orthologs:
Homo sapiens (human) : BCKDK (branched chain keto acid dehydrogenase kinase)  HGNC  Alliance
Mus musculus (house mouse) : Bckdk (branched chain ketoacid dehydrogenase kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bckdk (branched chain keto acid dehydrogenase kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : BCKDK (branched chain keto acid dehydrogenase kinase)
Canis lupus familiaris (dog) : BCKDK (branched chain keto acid dehydrogenase kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bckdk (branched chain keto acid dehydrogenase kinase)
Sus scrofa (pig) : BCKDK (branched chain keto acid dehydrogenase kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01199,351,628 - 199,356,299 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,351,628 - 199,356,881 (+)Ensembl
Rnor_5.01206,374,221 - 206,378,892 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,189,665 - 187,194,336 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11187,340,263 - 187,344,799 (+)NCBI
Celera1180,166,156 - 180,170,827 (+)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Bckdk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2198
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.