Gene: C5 (complement C5) Rattus norvegicus
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Symbol: C5
Name: complement C5
Description: Exhibits C5a anaphylatoxin chemotactic receptor binding activity; involved in several processes, including chemotaxis, glucose homeostasis, and negative regulation of transport; localizes to the extracellular space; used to study adult respiratory distress syndrome, asthma, and neutropenia; biomarker of brain edema; orthologous to human C5 (complement C5); PARTICIPATES IN coagulation cascade pathway; complement system pathway; prion disease pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: anaphylatoxin; C5a; complement component 5; Hc; RGD1561905
Orthologs:
Homo sapiens (human) : C5 (complement C5)  HGNC  Alliance
Mus musculus (house mouse) : Hc (hemolytic complement)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : C5 (complement C5)
Canis lupus familiaris (dog) : C5 (complement C5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101959685 (complement C5)
Sus scrofa (pig) : C5 (complement C5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0314,206,466 - 14,229,141 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0314,049,993 - 14,113,931 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0319,369,981 - 19,432,948 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0319,525,468 - 19,547,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4314,011,115 - 14,102,744 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1313,962,273 - 13,963,756 (-)NCBI
Celera312,987,748 - 13,080,508 (-)NCBICelera
Cytogenetic Map3p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on C5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2237
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.