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Gene: Ca4 (carbonic anhydrase 4) Rattus norvegicus
Symbol: Ca4
Name: carbonic anhydrase 4
Description: Exhibits carbonate dehydratase activity. Involved in animal organ development; response to drug; and response to steroid hormone. Localizes to the apical plasma membrane; sarcolemma; and sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 17. Orthologous to human CA4 (carbonic anhydrase 4); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CA-IV; Car4; carbonate dehydratase IV; carbonic anhydrase IV
Homo sapiens (human) : CA4 (carbonic anhydrase 4)  HGNC  Alliance
Mus musculus (house mouse) : Car4 (carbonic anhydrase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ca4 (carbonic anhydrase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CA4 (carbonic anhydrase 4)
Canis lupus familiaris (dog) : CA4 (carbonic anhydrase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ca4 (carbonic anhydrase 4)
Sus scrofa (pig) : CA4 (carbonic anhydrase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01072,272,286 - 72,281,069 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01072,173,022 - 72,188,138 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41073,229,211 - 73,237,707 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11073,243,580 - 73,252,077 (+)NCBI
Celera1068,755,736 - 68,764,294 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ca4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2242
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.