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Gene: Ddr1 (discoidin domain receptor tyrosine kinase 1) Rattus norvegicus
Symbol: Ddr1
Name: discoidin domain receptor tyrosine kinase 1
Description: Predicted to have collagen binding activity and protein tyrosine kinase collagen receptor activity. Involved in animal organ regeneration and skin development. Localizes to basolateral plasma membrane; brush border; and cytoplasm. Biomarker of congestive heart failure. Orthologous to human DDR1 (discoidin domain receptor tyrosine kinase 1); INTERACTS WITH 2-acetamidofluorene; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cak; CD167 antigen-like family member A; cell adhesion kinase; discoidin domain receptor family member 1; discoidin domain receptor family, member 1; discoidin receptor tyrosine kinase; Drd1; epithelial discoidin domain receptor 1; epithelial discoidin domain-containing receptor 1; neurotrophic tyrosine kinase receptor type 4; Neurotrophic tyrosine kinase receptor type 4 (cell adhesion kinase); protein-tyrosine kinase 3; protein-tyrosine kinase PTK-3; PTK3D; tyrosine kinase DDR; tyrosine-protein kinase CAK
Homo sapiens (human) : DDR1 (discoidin domain receptor tyrosine kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ddr1 (discoidin domain receptor family, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddr1 (discoidin domain receptor tyrosine kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DDR1 (discoidin domain receptor tyrosine kinase 1)
Canis lupus familiaris (dog) : DDR1 (discoidin domain receptor tyrosine kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddr1 (discoidin domain receptor tyrosine kinase 1)
Sus scrofa (pig) : DDR1 (discoidin domain receptor tyrosine kinase 1)
Chlorocebus sabaeus (African green monkey) : DDR1 (discoidin domain receptor tyrosine kinase 1)
Heterocephalus glaber (naked mole-rat) : Ddr1 (discoidin domain receptor tyrosine kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0203,553,430 - 3,574,959 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,552,929 - 3,575,780 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,652,154 - 5,671,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,194,265 - 3,214,611 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,202,454 - 3,214,838 (+)NCBI
Celera20470,029 - 489,383 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ddr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2252
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.