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Gene: Calm1 (calmodulin 1) Rattus norvegicus
Symbol: Calm1
Name: calmodulin 1
Description: Exhibits several functions, including enzyme binding activity; ion channel binding activity; and type 3 metabotropic glutamate receptor binding activity. Involved in several processes, including activation of adenylate cyclase activity; regulation of calcium ion transmembrane transporter activity; and regulation of synaptic vesicle cycle. Localizes to several cellular components, including growth cone; myelin sheath; and nucleus. Colocalizes with mitochondrial membrane and synaptic vesicle membrane. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 4; long QT syndrome 14; and long QT syndrome 15. Orthologous to several human genes including CALM1 (calmodulin 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; INTERACTS WITH (R)-lipoic acid; 1-naphthyl isothiocyanate; 2,4,6-trinitrotoluene.
Type: protein-coding
Also known as: Calm; calmodulin; Calmodulin 1 (phosphorylase kinase delta); Calmodulin 1 (phosphorylase kinase, delta); calmodulin I; calmodulin-1; caM; Cam1; CaMI
Homo sapiens (human) : CALM1 (calmodulin 1)  HGNC  Alliance
Mus musculus (house mouse) : Calm1 (calmodulin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Calm1 (calmodulin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CALM1 (calmodulin 1)
Canis lupus familiaris (dog) : CALM1 (calmodulin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101967074 (calmodulin)
Sus scrofa (pig) : CALM1 (calmodulin 1)
Chlorocebus sabaeus (African green monkey) : CALM1 (calmodulin 1)
Heterocephalus glaber (naked mole-rat) : Calm1 (calmodulin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06124,217,241 - 124,225,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6124,217,241 - 124,225,292 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06133,444,207 - 133,452,258 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46124,477,601 - 124,485,669 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16124,481,414 - 124,491,549 (+)NCBI
Celera6117,015,915 - 117,023,918 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Calm1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2257
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.