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Gene: Calm2 (calmodulin 2) Rattus norvegicus
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Symbol: Calm2
Name: calmodulin 2
Description: Exhibits several functions, including enzyme binding activity; ion channel binding activity; and nitric-oxide synthase regulator activity. Involved in several processes, including activation of adenylate cyclase activity; regulation of calcium ion transmembrane transporter activity; and regulation of synaptic vesicle cycle. Localizes to several cellular components, including growth cone; myelin sheath; and nucleus. Colocalizes with mitochondrial membrane and synaptic vesicle membrane. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 4; long QT syndrome 14; and long QT syndrome 15. Orthologous to several human genes including CALM1 (calmodulin 1); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; calcium/calcium-mediated signaling pathway; calcium/calmodulin dependent kinase 2 signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calmodulin; calmodulin 2 (phosphorylase kinase delta); calmodulin 2 (phosphorylase kinase, delta); calmodulin-2; caM; Cam2; Camb; CaMII
Orthologs:
Homo sapiens (human) : CALM2 (calmodulin 2)  HGNC  Alliance
Mus musculus (house mouse) : Calm2 (calmodulin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Calm2 (calmodulin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CALM2 (calmodulin 2)
Canis lupus familiaris (dog) : CALM2 (calmodulin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Calm2 (calmodulin 2)
Sus scrofa (pig) : CALM2 (calmodulin 2)
Chlorocebus sabaeus (African green monkey) : CALM2 (calmodulin 2)
Heterocephalus glaber (naked mole-rat) : Calm2 (calmodulin 2)
more info ...
Related Pseudogenes: Calm-ps1   Calm-ps2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0611,067,675 - 11,080,078 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1565,506,874 - 65,507,968 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0621,052,945 - 21,068,133 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4664,161,641 - 64,162,751 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11564,177,420 - 64,178,531 (-)NCBI
Celera66,842,934 - 6,855,590 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Calm2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2258
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.