Gene: Cbr1 (carbonyl reductase 1) Rattus norvegicus
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Symbol: Cbr1
Name: carbonyl reductase 1
Description: Exhibits carbonyl reductase (NADPH) activity; involved in several processes, including ovulation from ovarian follicle, phylloquinone catabolic process, and prostaglandin catabolic process; localizes to the microvillus, nucleus, and plasma membrane; biomarker of chronic kidney disease; orthologous to human CBR1 (carbonyl reductase 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 15-hydroxyprostaglandin dehydrogenase; 20-beta-hydroxysteroid dehydrogenase; carbonyl reductase; carbonyl reductase [NADPH] 1; Cbr; Cbr 1; MGC124927; NADPH-dependent carbonyl reductase 1; prostaglandin 9-ketoreductase; prostaglandin-E(2) 9-reductase
Orthologs:
Homo sapiens (human) : CBR1 (carbonyl reductase 1)  HGNC  Alliance
Mus musculus (house mouse) : Cbr1 (carbonyl reductase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cbr1 (carbonyl reductase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CBR1 (carbonyl reductase 1)
Canis lupus familiaris (dog) : LOC610164 (carbonyl reductase [NADPH] 1)
Sus scrofa (pig) : CBR1 (carbonyl reductase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01133,813,041 - 33,815,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01137,436,992 - 37,439,368 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41133,787,957 - 33,790,320 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11133,844,199 - 33,846,562 (+)NCBI
Celera1132,503,106 - 32,505,469 (+)NCBICelera
Cytogenetic Map11q11NCBI
RH 3.4 Map11248.5RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cbr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2286
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.