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Gene: LUZP6 (leucine zipper protein 6) Homo sapiens
Symbol: LUZP6
Name: leucine zipper protein 6
Description: A bi-cistronic transcript encodes the products of both the myotrophin and leucine zipper protein 6 genes, which are located on chromosome 7. A cryptic ORF at the 3' end of the myotrophin transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MPD6; MTPNUT; myeloproliferative disease-associated 6 kDa antigen; myeloproliferative disease-associated antigen, 6-kD; myeloproliferative disease-associated SEREX antigen; myotrophin 3'UTR transcript
Pan paniscus (bonobo/pygmy chimpanzee) : LUZP6 (leucine zipper protein 6)
Canis lupus familiaris (dog) : LUZP6 (leucine zipper protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Luzp6 (leucine zipper protein 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh387135,926,760 - 135,977,359 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377135,611,503 - 135,662,204 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367135,611,503 - 135,662,204 (-)NCBINCBI36hg18NCBI36
Celera7130,348,855 - 130,399,560 (-)NCBI
Cytogenetic Map7q33NCBI
HuRef7129,914,553 - 129,965,190 (-)NCBIHuRef
CHM1_17135,545,252 - 135,596,008 (-)NCBICHM1_1
CRA_TCAGchr7v27134,955,940 - 135,006,645 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LUZP6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2290193
Created: 2008-02-29
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.