Gene: Ccne1 (cyclin E1) Rattus norvegicus
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Symbol: Ccne1
Name: cyclin E1
Description: Exhibits protein kinase binding activity; predicted to contribute to protein kinase activity; involved in several processes, including animal organ development, response to nutrient, and response to steroid hormone; localizes to the centrosome, cytoplasm, and nucleus; biomarker of hepatocellular carcinoma, hypertension, and ovarian carcinoma; orthologous to human CCNE1 (cyclin E1); PARTICIPATES IN G1/S transition pathway; mTOR signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH (-)-citrinin; (R)-mevalonic acid; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ccne; CYCLE; cyclin E; G1/S-specific cyclin-E1
Orthologs:
Homo sapiens (human) : CCNE1 (cyclin E1)  HGNC  Alliance
Mus musculus (house mouse) : Ccne1 (cyclin E1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccne1 (cyclin E1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCNE1 (cyclin E1)
Canis lupus familiaris (dog) : CCNE1 (cyclin E1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccne1 (cyclin E1)
Sus scrofa (pig) : CCNE1 (cyclin E1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0194,485,830 - 94,495,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0195,575,136 - 95,584,387 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4190,568,189 - 90,577,426 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1190,646,304 - 90,655,502 (-)NCBI
Celera185,114,968 - 85,124,206 (-)NCBICelera
Cytogenetic Map1q21NCBI
RH 3.4 Map1885.7RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ccne1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2294
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.