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Gene: Tigit (T cell immunoreceptor with Ig and ITIM domains) Mus musculus
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Symbol: Tigit
Name: T cell immunoreceptor with Ig and ITIM domains
Description: Exhibits signaling receptor binding activity. Involved in negative regulation of T cell activation. Predicted to localize to the cell surface. Orthologous to human TIGIT (T cell immunoreceptor with Ig and ITIM domains); INTERACTS WITH silicon dioxide; titanium dioxide; aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ENSMUSG00000071552; T-cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; Vstm3
Orthologs:
Homo sapiens (human) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tigit (T cell immunoreceptor with Ig and ITIM domains)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tigit (T cell immunoreceptor with Ig and ITIM domains)
Pan paniscus (bonobo/pygmy chimpanzee) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Canis lupus familiaris (dog) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tigit (T cell immunoreceptor with Ig and ITIM domains)
Sus scrofa (pig) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Chlorocebus sabaeus (African green monkey) : TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Heterocephalus glaber (naked mole-rat) : Tigit (T cell immunoreceptor with Ig and ITIM domains)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1643,648,867 - 43,664,146 (-)EnsemblGRCm38mm10GRCm38
GRCm381643,626,137 - 43,665,125 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371643,648,974 - 43,664,297 (-)NCBIGRCm37mm9NCBIm37
MGSCv361643,649,114 - 43,664,297 (-)NCBImm8
Celera1644,003,410 - 44,018,650 (-)NCBICelera
Cytogenetic Map16B4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tigit
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2294384
Created: 2008-06-20
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.