Gene: Cd28 (Cd28 molecule) Rattus norvegicus
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Symbol: Cd28
Name: Cd28 molecule
Description: Exhibits protein homodimerization activity; involved in T cell activation and T cell costimulation; localizes to the membrane raft; used to study lymphopenia; orthologous to human CD28 (CD28 molecule); PARTICIPATES IN allograft rejection pathway; autoimmune thyroiditis pathway; graft-versus-host disease pathway; INTERACTS WITH (RS)-amphetamine; 2-amino-2-deoxy-D-glucopyranose; aldehydo-D-glucosamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD28 antigen; CD28RNA; T-cell-specific surface glycoprotein CD28
Orthologs:
Homo sapiens (human) : CD28 (CD28 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd28 (CD28 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd28 (CD28 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD28 (CD28 molecule)
Canis lupus familiaris (dog) : CD28 (CD28 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd28 (CD28 molecule)
Sus scrofa (pig) : CD28 (CD28 molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0967,546,408 - 67,573,858 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0967,358,994 - 67,386,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4959,342,273 - 59,367,743 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1959,489,254 - 59,514,725 (+)NCBI
Celera959,589,124 - 59,614,592 (+)NCBICelera
Cytogenetic Map9q32NCBI
RH 3.4 Map9504.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cd28
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2299
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.