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Gene: RSPH10B2 (radial spoke head 10 homolog B2) Homo sapiens
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Symbol: RSPH10B2
Name: radial spoke head 10 homolog B2
Description: This gene encodes a protein component of the radial spoke head in flagella and motile cilia. Eukaryotic flagella and motile cilia share a common 9 + 2 structure, in which nine peripheral microtubule doublets (MTDs) surround a central-pair of microtubules (CP), with radial spokes connecting the MTDs to the CP. The radial spoke is a multi-protein complex that works as a mechanochemical transducer between the CP and the MTDs. The radial spoke contributes to the regulation of the activity of dynein motors, and thus to flagellar motility. PMID: 22754630 provides a good review of radial spokes. [provided by RefSeq, Jul 2017]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ36092; FLJ54347; FLJ95901; radial spoke head 10 homolog B; radial spoke head 10 homolog B-like; radial spoke head 10 homolog B2 (Chlamydomonas); RSPH10B
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3876,754,109 - 6,798,775 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3776,793,732 - 6,838,396 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3676,760,265 - 6,804,921 (+)NCBINCBI36hg18NCBI36
Cytogenetic Map7p22.1NCBI
CHM1_176,793,330 - 6,838,017 (+)NCBICHM1_1
CRA_TCAGchr7v276,840,778 - 6,885,434NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RSPH10B2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2300131
Created: 2008-09-05
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.