Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RSPH10B2 (radial spoke head 10 homolog B2) Homo sapiens
Symbol: RSPH10B2
Name: radial spoke head 10 homolog B2
Description: This gene encodes a protein component of the radial spoke head in flagella and motile cilia. Eukaryotic flagella and motile cilia share a common 9 + 2 structure, in which nine peripheral microtubule doublets (MTDs) surround a central-pair of microtubules (CP), with radial spokes connecting the MTDs to the CP. The radial spoke is a multi-protein complex that works as a mechanochemical transducer between the CP and the MTDs. The radial spoke contributes to the regulation of the activity of dynein motors, and thus to flagellar motility. PMID: 22754630 provides a good review of radial spokes. [provided by RefSeq, Jul 2017]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ36092; FLJ54347; FLJ95901; radial spoke head 10 homolog B; radial spoke head 10 homolog B-like; radial spoke head 10 homolog B2 (Chlamydomonas); RSPH10B
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3876,754,109 - 6,798,775 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3776,793,732 - 6,838,396 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3676,760,265 - 6,804,921 (+)NCBINCBI36hg18NCBI36
Cytogenetic Map7p22.1NCBI
CHM1_176,793,330 - 6,838,017 (+)NCBICHM1_1
CRA_TCAGchr7v276,840,778 - 6,885,434NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RSPH10B2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2300131
Created: 2008-09-05
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.