TRP-AGG2-3 (tRNA-Pro (anticodon AGG) 2-3) - Chinchilla Research Resource Database

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Gene: TRP-AGG2-3 (tRNA-Pro (anticodon AGG) 2-3) Homo sapiens

Analyze

General
Array IDs
References

Symbol:

TRP-AGG2-3

Name:

tRNA-Pro (anticodon AGG) 2-3

Description:

Type:

trna

RefSeq Status:

MODEL

Also known as:

transfer RNA-Pro (AGG) 2-3; TRNAP15; TRP-AGG2-8

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	128,783,450 - 128,783,521 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	128,423,504 - 128,423,575 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	7	q32.1	NCBI
HuRef	7	122,784,301 - 122,784,372 (+)	NCBI		HuRef
CHM1_1	7	128,356,739 - 128,356,810 (+)	NCBI		CHM1_1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation (Toggle Annotation Detail/Summary View)

References - uncurated

PubMed

18984615

Genomics

Position Markers

GDB:1318698

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	7	128,422,603 - 128,422,669	UniSTS	GRCh37
Build 36	7	128,209,839 - 128,209,905	RGD	NCBI36
Celera	7	123,218,357 - 123,218,423	RGD
Cytogenetic Map	7	q32.1	UniSTS
HuRef	7	122,783,400 - 122,783,466	UniSTS
CRA_TCAGchr7v2	7	127,805,587 - 127,805,653	UniSTS

Expression

Sequence

Nucleotide Sequences

GenBank Nucleotide	AC024952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HG983985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1	copy number loss	See cases [RCV000135401]	Chr7:54185..159282390 [GRCh38] Chr7:54185..159075079 [GRCh37] Chr7:149268..158767840 [NCBI36] Chr7:7p22.3-q36.3	pathogenic
GRCh38/hg38 7q21.3-36.3(chr7:97419852-158923762)x3	copy number gain	See cases [RCV000136717]	Chr7:97419852..158923762 [GRCh38] Chr7:97049164..158716453 [GRCh37] Chr7:96887100..158409214 [NCBI36] Chr7:7q21.3-36.3	pathogenic
GRCh38/hg38 7q31.2-33(chr7:117326805-134790689)x1	copy number loss	See cases [RCV000138226]	Chr7:117326805..134790689 [GRCh38] Chr7:116966859..134475440 [GRCh37] Chr7:116754095..134125980 [NCBI36] Chr7:7q31.2-33	pathogenic
GRCh38/hg38 7q31.32-36.3(chr7:121863759-159335865)x3	copy number gain	See cases [RCV000138847]	Chr7:121863759..159335865 [GRCh38] Chr7:121503813..159128555 [GRCh37] Chr7:121291049..158821316 [NCBI36] Chr7:7q31.32-36.3	pathogenic
GRCh38/hg38 7q31.2-36.3(chr7:115459015-159325817)x3	copy number gain	See cases [RCV000141413]	Chr7:115459015..159325817 [GRCh38] Chr7:115099069..159118507 [GRCh37] Chr7:114886305..158811268 [NCBI36] Chr7:7q31.2-36.3	pathogenic
GRCh38/hg38 7q32.1(chr7:127817826-129237503)x3	copy number gain	See cases [RCV000142106]	Chr7:127817826..129237503 [GRCh38] Chr7:127457880..128877344 [GRCh37] Chr7:127245116..128664580 [NCBI36] Chr7:7q32.1	likely benign\|uncertain significance
GRCh38/hg38 7q31.33-33(chr7:124170657-134163594)x1	copy number loss	See cases [RCV000142552]	Chr7:124170657..134163594 [GRCh38] Chr7:123810711..133848346 [GRCh37] Chr7:123597947..133498886 [NCBI36] Chr7:7q31.33-33	pathogenic
GRCh38/hg38 7q31.32-32.1(chr7:122018122-128907727)x1	copy number loss	See cases [RCV000142521]	Chr7:122018122..128907727 [GRCh38] Chr7:121658176..128547780 [GRCh37] Chr7:121445412..128335016 [NCBI36] Chr7:7q31.32-32.1	pathogenic
GRCh38/hg38 7q32.1-33(chr7:128747478-134018250)x3	copy number gain	Global developmental delay [RCV000051072]\|See cases [RCV000051072]	Chr7:128747478..134018250 [GRCh38] Chr7:128387532..133703003 [GRCh37] Chr7:128174768..133353543 [NCBI36] Chr7:7q32.1-33	pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1	copy number loss	Ambiguous genitalia [RCV000052250]\|See cases [RCV000052250]	Chr7:53985..159282531 [GRCh38] Chr7:53985..159075220 [GRCh37] Chr7:149068..158767981 [NCBI36] Chr7:7p22.3-q36.3	pathogenic
GRCh38/hg38 7q31.33-32.3(chr7:126859732-132750936)x1	copy number loss	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054171]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054171]\|See cases [RCV000054171]	Chr7:126859732..132750936 [GRCh38] Chr7:126499786..132435696 [GRCh37] Chr7:126287022..132086236 [NCBI36] Chr7:7q31.33-32.3	pathogenic

Additional Information

External Database Links

Database	Acc Id	Source(s)
COSMIC	TRP-AGG2-3	COSMIC
GTEx	TRP-AGG2-3	GTEx
HGNC ID	HGNC:34840	ENTREZGENE
Human Proteome Map	TRP-AGG2-3	Human Proteome Map
NCBI Gene	100189276	ENTREZGENE
PharmGKB	PA164727123	PharmGKB

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-09	TRP-AGG2-3	tRNA-Pro (anticodon AGG) 2-3		transfer RNA-Pro (AGG) 2-3	Symbol and/or name change	5135510	APPROVED
2016-02-29	TRP-AGG2-3	transfer RNA-Pro (AGG) 2-3	TRP-AGG2-8	transfer RNA-Pro (AGG) 2-8	Symbol and/or name change	5135510	APPROVED
2014-06-24	TRP-AGG2-8	transfer RNA-Pro (AGG) 2-8	TRNAP15	transfer RNA proline 15 (anticodon AGG)	Symbol and/or name change	5135510	APPROVED

More on TRP-AGG2-3
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: hg19 hg38
	HGNC Report
	NCBI Genome Data Viewer

CRRD Object Information
CRRD ID:	2300701
Created:	2008-09-19
Species:	Homo sapiens
Last Modified:	2019-11-26
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.