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Gene: Cd247 (Cd247 molecule) Rattus norvegicus
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Symbol: Cd247
Name: Cd247 molecule
CRRD ID: 2305
Description: Predicted to have identical protein binding activity and protein tyrosine kinase binding activity. Involved in cell surface receptor signaling pathway. Localizes to T cell receptor complex. Human ortholog(s) of this gene implicated in immunodeficiency 25. Orthologous to human CD247 (CD247 molecule); PARTICIPATES IN interleukin-12 signaling pathway; Chagas disease pathway; T cell receptor signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD247 antigen; CD3 antigen, zeta polypeptide; Cd3z; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell surface glycoprotein CD3 zeta chain; TCRzeta
Orthologs:
Homo sapiens (human) : CD247 (CD247 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd247 (CD247 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd247 (CD247 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD247 (CD247 molecule)
Canis lupus familiaris (dog) : CD247 (CD247 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd247 (CD247 molecule)
Sus scrofa (pig) : CD247 (CD247 molecule)
Chlorocebus sabaeus (African green monkey) : CD247 (CD247 molecule)
Heterocephalus glaber (naked mole-rat) : Cd247 (CD247 molecule)
more info ...
Allele / Splice: Cd247em1Mcwi   Cd247em5Mcwi   Cd247em3Mcwi  
Genetic Models: SS-Cd247em3Mcwi SS-Cd247em1Mcwi SS-Cd247em5Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01383,996,045 - 84,071,408 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1383,996,080 - 84,071,400 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01388,876,046 - 88,951,003 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41381,515,383 - 81,594,699 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11381,529,570 - 81,608,887 (+)NCBI
Celera1377,754,426 - 77,829,099 (+)NCBICelera
Cytogenetic Map13q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cd247
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2305
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.