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Gene: CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2) Homo sapiens
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Symbol: CASTOR2
Name: cytosolic arginine sensor for mTORC1 subunit 2
Description: Exhibits identical protein binding activity. Involved in negative regulation of TORC1 signaling. Localizes to the cytosol. Colocalizes with the GATOR2 complex; PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; doxorubicin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cellular arginine sensor for mTORC1 protein 2; cytosolic arginine sensor for mTORC1 subunit 1; GATS protein like 2; GATS protein-like 1; GATS protein-like 2; GATS-like protein 1; GATS-like protein 2; GATSL1; GATSL2
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38774,964,693 - 75,031,531 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37774,807,605 - 74,867,341 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36774,645,541 - 74,706,426 (-)NCBINCBI36hg18NCBI36
Celera794,555,567 - 94,604,910 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef770,091,388 - 70,108,013 (+)NCBIHuRef
CHM1_1774,524,234 - 74,590,948 (+)NCBICHM1_1
CRA_TCAGchr7v2774,140,669 - 74,200,405 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CASTOR2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2306471
Created: 2009-04-17
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.