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Gene: CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2) Homo sapiens
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Symbol: CASTOR2
Name: cytosolic arginine sensor for mTORC1 subunit 2
Description: Exhibits identical protein binding activity. Involved in negative regulation of TORC1 signaling. Localizes to the cytosol. Colocalizes with the GATOR2 complex; PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; doxorubicin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cellular arginine sensor for mTORC1 protein 2; cytosolic arginine sensor for mTORC1 subunit 1; GATS protein like 2; GATS protein-like 1; GATS protein-like 2; GATS-like protein 1; GATS-like protein 2; GATSL1; GATSL2
Orthologs:
Mus musculus (house mouse) : Castor2 (cytosolic arginine sensor for mTORC1 subunit 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Castor2 (cytosolic arginine sensor for mTORC1 subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Castor2 (cytosolic arginine sensor for mTORC1 subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2)
Canis lupus familiaris (dog) : CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Castor2 (cytosolic arginine sensor for mTORC1 subunit 2)
Sus scrofa (pig) : CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38774,964,693 - 75,031,531 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37774,807,605 - 74,867,341 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36774,645,541 - 74,706,426 (-)NCBINCBI36hg18NCBI36
Celera794,555,567 - 94,604,910 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef770,091,388 - 70,108,013 (+)NCBIHuRef
CHM1_1774,524,234 - 74,590,948 (+)NCBICHM1_1
CRA_TCAGchr7v2774,140,669 - 74,200,405 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

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Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
  
More on CASTOR2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2306471
Created: 2009-04-17
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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