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Gene: Cd44 (CD44 molecule (Indian blood group)) Rattus norvegicus
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Symbol: Cd44
Name: CD44 molecule (Indian blood group)
Description: Exhibits epidermal growth factor receptor binding activity; phosphoprotein binding activity; and protein kinase binding activity. Predicted to contribute to cytokine binding activity and cytokine receptor activity. Involved in several processes, including blood vessel maturation; macrophage fusion; and positive regulation of neutrophil apoptotic process. Localizes to several cellular components, including apical plasma membrane; basolateral plasma membrane; and nucleus. Biomarker of borna disease and cholestasis. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); cholestasis; and prostate cancer. Orthologous to human CD44 (CD44 molecule (Indian blood group)); PARTICIPATES IN cell-extracellular matrix signaling pathway; INTERACTS WITH (+)-schisandrin B; (S)-colchicine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD44 antigen; CD44 antigen isoform d6-12; CD44 antigen isoform d6-13; CD44 antigen isoform d6-15; Cd44 molecule; CD44A; cell surface glycoprotein CD44 (hyaluronate binding protein); ECMR-III; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; hermes antigen; HUTCH-I; hyaluronate receptor; METAA; MGC124941; PGP-1; PGP-I; phagocytic glycoprotein 1; phagocytic glycoprotein I; RHAMM
Orthologs:
Homo sapiens (human) : CD44 (CD44 molecule (Indian blood group))  HGNC  Alliance
Mus musculus (house mouse) : Cd44 (CD44 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd44 (CD44 molecule (Indian blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : CD44 (CD44 molecule (Indian blood group))
Canis lupus familiaris (dog) : CD44 (CD44 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd44 (CD44 molecule (Indian blood group))
Sus scrofa (pig) : CD44 (CD44 molecule)
Chlorocebus sabaeus (African green monkey) : CD44 (CD44 molecule (Indian blood group))
Heterocephalus glaber (naked mole-rat) : Cd44 (CD44 molecule (Indian blood group))
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0392,695,083 - 92,783,820 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl392,696,313 - 92,783,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0399,338,248 - 99,426,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4388,022,962 - 88,110,352 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1387,919,389 - 88,006,780 (-)NCBI
Celera388,236,830 - 88,324,125 (-)NCBICelera
Cytogenetic Map3q32NCBI
RH 3.4 Map3656.5RGD
RH 3.4 Map3669.0RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cd44
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2307
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-04-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.