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Gene: CMC4 (C-X9-C motif containing 4) Homo sapiens
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Symbol: CMC4
Name: C-X9-C motif containing 4
Description: This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the downstream 8 kDa protein that localizes to mitochondria.[provided by RefSeq, Mar 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-x(9)-C motif containing 4; C-x(9)-C motif containing 4 homolog; C6.1B; cx9C motif-containing protein 4; mature T-cell proliferation 1 neighbor protein; mature T-cell proliferation 1, isoform p8; mature T-cell proliferation-1 type A; MGC2069; MTCP-1 type A; MTCP1; MTCP1B; MTCP1NB; p8; p8MTCP1; protein p8 MTCP-1
Orthologs:
Mus musculus (house mouse) : Cmc4 (C-x(9)-C motif containing 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cmc4 (C-X9-C motif containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cmc4 (C-X9-C motif containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CMC4 (C-X9-C motif containing 4)
Canis lupus familiaris (dog) : CMC4 (C-X9-C motif containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cmc4 (C-X9-C motif containing 4)
Sus scrofa (pig) : CMC4 (C-X9-C motif containing 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: MTCP1 (Gene ID: 4515) and CMC4 (Gene ID: 100272147) share the MTCP1 symbol/alias in common. MTCP1 has been used as an alternative name for C-X9-C motif containing 4 (CMC4), which can be confused with the official symbol for mature T cell proliferation 1 (MTCP1). [06 Jul 2018]; Note: Prior to build 37.1, geneID:4515 (MTCP1) was annotated as a single locus expressing transcripts with two distinct protein products. The locus was subsequently split into two geneIDs, with geneID:4515 representing the upstream locus (MTCP1, aka isoform p13) and geneID:100272147 representing the downstream locus (MTCP1NB, aka isoform p8). [13 Feb 2013]
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X155,061,622 - 155,071,136 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X154,289,897 - 154,299,547 (-)NCBIGRCh37GRCh37hg19GRCh37
CeleraX154,448,614 - 154,458,264 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,835,131 - 142,844,484 (-)NCBIHuRef
CHM1_1X154,201,524 - 154,211,174 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CMC4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2308876
Created: 2009-06-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.