Gene: Cd74 (CD74 molecule) Rattus norvegicus
Symbol: Cd74
Name: CD74 molecule
Description: Predicted to have several functions, including amyloid-beta binding activity, cytokine receptor activity, and signaling receptor binding activity; involved in activation of MAPK activity and cell population proliferation; predicted to colocalize with the MHC class II protein complex; orthologous to human CD74 (CD74 molecule); PARTICIPATES IN antigen processing and presentation pathway; tuberculosis pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD74 antigen (invariant polpypeptide of major histocompatibility class II antigen-associated); CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); Cd74 molecule, major histocompatibility complex, class II invariant chain; H-2 class II histocompatibility antigen gamma chain; ia antigen-associated invariant chain; ii; INVG34; MHC class II-associated invariant chain
Homo sapiens (human) : CD74 (CD74 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd74 (CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd74 (CD74 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD74 (CD74 molecule)
Canis lupus familiaris (dog) : CD74 (CD74 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd74 (CD74 molecule)
Sus scrofa (pig) : CD74 (CD74 molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01856,071,420 - 56,080,851 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01855,305,827 - 55,315,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41856,756,511 - 56,765,711 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11856,828,786 - 56,837,940 (+)NCBI
Celera1852,411,586 - 52,420,786 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
RH 3.4 Map18525.0RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Cd74
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2313
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.