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Gene: Oca2 (OCA2 melanosomal transmembrane protein) Rattus norvegicus
Symbol: Oca2
Name: OCA2 melanosomal transmembrane protein
Description: Predicted to be involved in several processes, including cell population proliferation; melanin biosynthetic process; and melanocyte differentiation. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in actinic keratosis; oculocutaneous albinism type II; pigmentation disease; skin cancer (multiple); and squamous cell carcinoma. Orthologous to human OCA2 (OCA2 melanosomal transmembrane protein); INTERACTS WITH 1-naphthyl isothiocyanate; paracetamol; 5,6-dihydroxyindole-2-carboxylic acid (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC100365773; oculocutaneous albinism II; p; pink-eyed dilution-like; uncharacterized protein LOC100365773
Homo sapiens (human) : OCA2 (OCA2 melanosomal transmembrane protein)  HGNC  Alliance
Mus musculus (house mouse) : Oca2 (oculocutaneous albinism II)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oca2 (OCA2 melanosomal transmembrane protein)
Pan paniscus (bonobo/pygmy chimpanzee) : OCA2 (OCA2 melanosomal transmembrane protein)
Canis lupus familiaris (dog) : OCA2 (OCA2 melanosomal transmembrane protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oca2 (OCA2 melanosomal transmembrane protein)
Sus scrofa (pig) : OCA2 (OCA2 melanosomal transmembrane protein)
more info ...
Is Marker For: Strains:   KHR/Kyo   KHR/Kyo-/+   KHR/Kyo-/-  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01114,661,970 - 114,987,433 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01115,720,909 - 115,991,040 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01115,683,593 - 115,683,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1101,324,224 - 101,633,838 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Oca2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2318412
Created: 2010-05-05
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.