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Gene: Oca2 (OCA2 melanosomal transmembrane protein) Rattus norvegicus
Symbol: Oca2
Name: OCA2 melanosomal transmembrane protein
CRRD ID: 2318412
Description: Predicted to be involved in several processes, including melanin biosynthetic process; melanocyte differentiation; and spermatid development. Predicted to localize to bounding membrane of organelle and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in actinic keratosis; oculocutaneous albinism type II; pigmentation disease; skin cancer (multiple); and squamous cell carcinoma. Orthologous to human OCA2 (OCA2 melanosomal transmembrane protein); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC100365773; oculocutaneous albinism II; p; pink-eyed dilution-like; uncharacterized protein LOC100365773
Homo sapiens (human) : OCA2 (OCA2 melanosomal transmembrane protein)  HGNC  Alliance
Mus musculus (house mouse) : Oca2 (oculocutaneous albinism II)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oca2 (OCA2 melanosomal transmembrane protein)
Pan paniscus (bonobo/pygmy chimpanzee) : OCA2 (OCA2 melanosomal transmembrane protein)
Canis lupus familiaris (dog) : OCA2 (OCA2 melanosomal transmembrane protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oca2 (OCA2 melanosomal transmembrane protein)
Sus scrofa (pig) : OCA2 (OCA2 melanosomal transmembrane protein)
Chlorocebus sabaeus (African green monkey) : OCA2 (OCA2 melanosomal transmembrane protein)
Heterocephalus glaber (naked mole-rat) : Oca2 (OCA2 melanosomal transmembrane protein)
more info ...
Is Marker For: Strains:   KHR/Kyo   KHR/Kyo-/+   KHR/Kyo-/-  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01114,661,970 - 114,987,433 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1114,679,537 - 114,987,433 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01115,683,593 - 115,683,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01115,720,909 - 115,991,040 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1101,324,224 - 101,633,838 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Oca2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2318412
Created: 2010-05-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.