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Gene: LOC100364500 (RT1 class I, locus CE11-like) Rattus norvegicus
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Symbol: LOC100364500
Name: RT1 class I, locus CE11-like
Description: Predicted to have several functions, including T cell receptor binding activity; beta-2-microglobulin binding activity; and peptide antigen binding activity. Predicted to be involved in several processes, including positive regulation of T cell activation; regulation of lymphocyte mediated immunity; and response to bacterium. Predicted to localize to several cellular components, including the Golgi medial cisterna; MHC class I protein complex; and endoplasmic reticulum. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; asthma (multiple); bone inflammation disease (multiple); eye disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A); HLA-B (major histocompatibility complex, class I, B); and HLA-E (major histocompatibility complex, class I, E); INTERACTS WITH 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: class I histocompatibility antigen, Non-RT1.A alpha-1 chain; RT1 class I histocompatibility antigen, AA alpha chain
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0202,704,153 - 2,707,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0204,805,474 - 4,808,452 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on LOC100364500
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2320860
Created: 2010-05-05
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.