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Gene: LOC100364500 (RT1 class I, locus CE11-like) Rattus norvegicus
Symbol: LOC100364500
Name: RT1 class I, locus CE11-like
CRRD ID: 2320860
Description: Predicted to have several functions, including TAP complex binding activity; beta-2-microglobulin binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway; regulation of lymphocyte mediated immunity; and response to bacterium. Predicted to localize to several cellular components, including Golgi medial cisterna; MHC class I protein complex; and endoplasmic reticulum. Human ortholog(s) of this gene implicated in Stevens-Johnson syndrome; acquired immunodeficiency syndrome; tuberculosis; and vulva cancer. Orthologous to human HLA-A (major histocompatibility complex, class I, A); PARTICIPATES IN interleukin-12 signaling pathway; INTERACTS WITH 1,2-dichloroethane (ortholog); 1,2-dimethylhydrazine (ortholog); 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: class I histocompatibility antigen, Non-RT1.A alpha-1 chain; RT1 class I histocompatibility antigen, AA alpha chain
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0202,704,153 - 2,707,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,704,148 - 2,707,120 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0204,805,474 - 4,808,452 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on LOC100364500
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2320860
Created: 2010-05-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.