Gene: Fbxw7 (F-box and WD repeat domain containing 7) Rattus norvegicus
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Symbol: Fbxw7
Name: F-box and WD repeat domain containing 7
Description: Predicted to have several functions, including cyclin binding activity, identical protein binding activity, and phosphothreonine residue binding activity; predicted to be involved in several processes, including cellular protein metabolic process, negative regulation of macromolecule metabolic process, and positive regulation of cellular metabolic process; predicted to localize to the cytoplasm, intracellular organelle, and ubiquitin ligase complex; orthologous to human FBXW7 (F-box and WD repeat domain containing 7); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH (-)-demecolcine (ortholog); 17alpha-ethynylestradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase; F-box and WD-40 domain protein 7; F-box/WD repeat-containing protein 7; LOC100360914
Orthologs:
Homo sapiens (human) : FBXW7 (F-box and WD repeat domain containing 7)  HGNC  Alliance
Mus musculus (house mouse) : Fbxw7 (F-box and WD-40 domain protein 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw7 (F-box and WD repeat domain containing 7)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW7 (F-box and WD repeat domain containing 7)
Canis lupus familiaris (dog) : FBXW7 (F-box and WD repeat domain containing 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw7 (F-box and WD repeat domain containing 7)
Sus scrofa (pig) : FBXW7 (F-box and WD repeat domain containing 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02184,230,191 - 184,309,805 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02203,633,724 - 203,708,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42176,675,226 - 176,750,737 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2164,144,641 - 164,303,043 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fbxw7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2321145
Created: 2010-05-05
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.