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Gene: Flt3lg (Fms related receptor tyrosine kinase 3 ligand) Rattus norvegicus
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Symbol: Flt3lg
Name: Fms related receptor tyrosine kinase 3 ligand
Description: Predicted to have protein homodimerization activity and receptor tyrosine kinase binding activity. Involved in positive regulation of natural killer cell proliferation. Predicted to localize to extracellular space and intrinsic component of external side of plasma membrane. Used to study pancreatic cancer. Human ortholog(s) of this gene implicated in colon carcinoma; glioblastoma multiforme; and malignant glioma. Orthologous to human FLT3LG (fms related receptor tyrosine kinase 3 ligand); INTERACTS WITH bisphenol A; (+)-catechin (ortholog); 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fms-related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand-like; LOC100363556; LOC102547607; LOC103691111; rCG54594-like; uncharacterized LOC103691111
Orthologs:
Homo sapiens (human) : FLT3LG (fms related receptor tyrosine kinase 3 ligand)  HGNC  Alliance
Mus musculus (house mouse) : Flt3l (FMS-like tyrosine kinase 3 ligand)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flt3lg (fms related receptor tyrosine kinase 3 ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : FLT3LG (fms related receptor tyrosine kinase 3 ligand)
Canis lupus familiaris (dog) : FLT3LG (fms related receptor tyrosine kinase 3 ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flt3lg (fms related receptor tyrosine kinase 3 ligand)
Chlorocebus sabaeus (African green monkey) : FLT3LG (fms related receptor tyrosine kinase 3 ligand)
Heterocephalus glaber (naked mole-rat) : Flt3lg (fms related receptor tyrosine kinase 3 ligand)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01101,126,006 - 101,131,413 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,124,479 - 101,131,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,190,086 - 102,197,519 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,607,131 - 95,611,290 (-)NCBIRGSC3.4rn4RGSC3.4
Celera189,873,472 - 89,878,870 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Flt3lg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2322792
Created: 2010-05-06
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.