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Gene: Nt5c2 (5'-nucleotidase, cytosolic II) Rattus norvegicus
Symbol: Nt5c2
Name: 5'-nucleotidase, cytosolic II
Description: Exhibits 5'-nucleotidase activity. Involved in IMP metabolic process and adenosine metabolic process. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 1-naphthyl isothiocyanate; endosulfan; ketamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: cytosolic purine 5'-nucleotidase; LOC100363253; LOC294016
Homo sapiens (human) : NT5C2 (5'-nucleotidase, cytosolic II)  HGNC  Alliance
Mus musculus (house mouse) : Nt5c2 (5'-nucleotidase, cytosolic II)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nt5c2 (5'-nucleotidase, cytosolic II)
Pan paniscus (bonobo/pygmy chimpanzee) : NT5C2 (5'-nucleotidase, cytosolic II)
Canis lupus familiaris (dog) : NT5C2 (5'-nucleotidase, cytosolic II)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nt5c2 (5'-nucleotidase, cytosolic II)
Sus scrofa (pig) : NT5C2 (5'-nucleotidase, cytosolic II)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01266,652,966 - 266,782,935 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01274,086,763 - 274,213,322 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41252,204,106 - 252,329,479 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11252,468,096 - 252,541,637 (-)NCBI
Celera1241,538,262 - 241,668,557 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nt5c2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2323387
Created: 2010-05-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.