Gene: Cdkl5 (cyclin-dependent kinase-like 5) Rattus norvegicus
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Symbol: Cdkl5
Name: cyclin-dependent kinase-like 5
Description: Exhibits Rac GTPase binding activity; involved in generation of neurons and positive regulation of GTPase activity; localizes to several cellular components, including the cytoplasm, glutamatergic synapse, and neuron projection; colocalizes with the ruffle membrane; orthologous to human CDKL5 (cyclin dependent kinase like 5); INTERACTS WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; methimazole.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC100362725
Orthologs:
Homo sapiens (human) : CDKL5 (cyclin dependent kinase like 5)  HGNC  Alliance
Mus musculus (house mouse) : Cdkl5 (cyclin-dependent kinase-like 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdkl5 (cyclin dependent kinase like 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CDKL5 (cyclin dependent kinase like 5)
Canis lupus familiaris (dog) : CDKL5 (cyclin dependent kinase like 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdkl5 (cyclin dependent kinase like 5)
Sus scrofa (pig) : CDKL5 (cyclin dependent kinase like 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X35,536,396 - 35,773,204 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X35,864,921 - 36,102,409 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X55,033,499 - 55,228,646 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX34,451,035 - 34,675,154 (+)NCBICelera
Cytogenetic MapXq14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cdkl5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2324133
Created: 2010-05-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.