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Gene: Tiam2 (TIAM Rac1 associated GEF 2) Rattus norvegicus
Symbol: Tiam2
Name: TIAM Rac1 associated GEF 2
Description: Predicted to have GTPase activator activity and Rac guanyl-nucleotide exchange factor activity. Predicted to be involved in activation of GTPase activity; positive regulation of axonogenesis; and small GTPase mediated signal transduction. Predicted to localize to cytoplasm; membrane; and synapse. Orthologous to human TIAM2 (TIAM Rac1 associated GEF 2); INTERACTS WITH cocaine; endosulfan; genistein.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC100362710; T-cell lymphoma invasion and metastasis 2; T-lymphoma invasion and metastasis-inducing protein 2
Homo sapiens (human) : TIAM2 (TIAM Rac1 associated GEF 2)  HGNC  Alliance
Mus musculus (house mouse) : Tiam2 (T cell lymphoma invasion and metastasis 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tiam2 (TIAM Rac1 associated GEF 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TIAM2 (TIAM Rac1 associated GEF 2)
Canis lupus familiaris (dog) : TIAM2 (TIAM Rac1 associated GEF 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tiam2 (TIAM Rac1 associated GEF 2)
Sus scrofa (pig) : TIAM2 (TIAM Rac1 associated GEF 2)
Chlorocebus sabaeus (African green monkey) : TIAM2 (TIAM Rac1 associated GEF 2)
Heterocephalus glaber (naked mole-rat) : Tiam2 (TIAM Rac1 associated GEF 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0144,232,520 - 44,433,450 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl144,311,513 - 44,433,193 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0145,562,714 - 45,763,294 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4138,479,385 - 38,514,359 (+)NCBIRGSC3.4rn4RGSC3.4
Celera139,555,701 - 39,754,110 (+)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tiam2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2324148
Created: 2010-05-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.