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Gene: Tiam2 (TIAM Rac1 associated GEF 2) Rattus norvegicus
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Symbol: Tiam2
Name: TIAM Rac1 associated GEF 2
Description: Predicted to have GTPase activator activity and Rac guanyl-nucleotide exchange factor activity. Predicted to be involved in activation of GTPase activity; positive regulation of axonogenesis; and small GTPase mediated signal transduction. Predicted to localize to cytoplasm; membrane; and synapse. Orthologous to human TIAM2 (TIAM Rac1 associated GEF 2); INTERACTS WITH cocaine; endosulfan; genistein.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC100362710; T-cell lymphoma invasion and metastasis 2; T-lymphoma invasion and metastasis-inducing protein 2
Orthologs:
Homo sapiens (human) : TIAM2 (TIAM Rac1 associated GEF 2)  HGNC  Alliance
Mus musculus (house mouse) : Tiam2 (T cell lymphoma invasion and metastasis 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tiam2 (TIAM Rac1 associated GEF 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TIAM2 (TIAM Rac1 associated GEF 2)
Canis lupus familiaris (dog) : TIAM2 (TIAM Rac1 associated GEF 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tiam2 (TIAM Rac1 associated GEF 2)
Sus scrofa (pig) : TIAM2 (TIAM Rac1 associated GEF 2)
Chlorocebus sabaeus (African green monkey) : TIAM2 (TIAM Rac1 associated GEF 2)
Heterocephalus glaber (naked mole-rat) : Tiam2 (TIAM Rac1 associated GEF 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0144,232,520 - 44,433,450 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl144,311,513 - 44,433,193 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0145,562,714 - 45,763,294 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4138,479,385 - 38,514,359 (+)NCBIRGSC3.4rn4RGSC3.4
Celera139,555,701 - 39,754,110 (+)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tiam2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2324148
Created: 2010-05-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.