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Gene: Chga (chromogranin A) Rattus norvegicus
Symbol: Chga
Name: chromogranin A
Description: Involved in several processes, including adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation; positive regulation of signal transduction; and regulation of heart contraction. Localizes to chromaffin granule; extracellular space; and neuronal dense core vesicle. Biomarker of hypertension. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal failure; hypertension; and prostate cancer. Orthologous to human CHGA (chromogranin A); PARTICIPATES IN G protein mediated signaling pathway; INTERACTS WITH (S)-nicotine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cgA; chromogranin A (parathyroid secretory protein 1); Chromogranin A parathyroid secretory protein 1; chromogranin A precursor; Chromogranin A, parathyroid secretory protein 1; chromogranin A-like; chromogranin-A; MGC105435
Homo sapiens (human) : CHGA (chromogranin A)  HGNC  Alliance
Mus musculus (house mouse) : Chga (chromogranin A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chga (chromogranin A)
Pan paniscus (bonobo/pygmy chimpanzee) : CHGA (chromogranin A)
Canis lupus familiaris (dog) : CHGA (uncharacterized CHGA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chga (chromogranin A)
Sus scrofa (pig) : CHGA (chromogranin A)
Chlorocebus sabaeus (African green monkey) : CHGA (chromogranin A)
Heterocephalus glaber (naked mole-rat) : Chga (chromogranin A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06126,434,226 - 126,445,569 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6126,434,226 - 126,445,568 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06135,645,155 - 135,656,373 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.16126,825,283 - 126,836,311 (+)NCBI
Celera6119,184,838 - 119,196,152 (+)NCBICelera
Cytogenetic Map6q32NCBI
RH 3.4 Map6845.4RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chga
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2338
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.