Gene: Chrm1 (cholinergic receptor, muscarinic 1) Rattus norvegicus
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Symbol: Chrm1
Name: cholinergic receptor, muscarinic 1
Description: Exhibits G protein-coupled acetylcholine receptor activity; involved in G protein-coupled acetylcholine receptor signaling pathway, neuromuscular synaptic transmission, and positive regulation of intracellular protein transport; localizes to the glutamatergic synapse, intrinsic component of plasma membrane, and neuron projection; orthologous to human CHRM1 (cholinergic receptor muscarinic 1); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; G protein mediated signaling pathway via Galphaq family; calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cholinergic receptor muscarin 1; cholinergic receptor, muscarin 1; M1 muscarinic acetylcholine receptor; muscarinic acetylcholine receptor M1
Orthologs:
Homo sapiens (human) : CHRM1 (cholinergic receptor muscarinic 1)  HGNC  Alliance
Mus musculus (house mouse) : Chrm1 (cholinergic receptor, muscarinic 1, CNS)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrm1 (cholinergic receptor muscarinic 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRM1 (cholinergic receptor muscarinic 1)
Canis lupus familiaris (dog) : CHRM1 (cholinergic receptor muscarinic 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrm1 (cholinergic receptor muscarinic 1)
Sus scrofa (pig) : CHRM1 (cholinergic receptor muscarinic 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01224,869,087 - 224,885,101 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01231,806,335 - 231,822,359 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,351,738 - 211,353,120 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,510,167 - 211,511,550 (+)NCBI
Celera1203,093,639 - 203,095,021 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Chrm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2342
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.