Gene: Chrna7 (cholinergic receptor nicotinic alpha 7 subunit) Rattus norvegicus
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Symbol: Chrna7
Name: cholinergic receptor nicotinic alpha 7 subunit
Description: Exhibits several functions, including acetylcholine binding activity, acetylcholine-gated cation-selective channel activity, and enzyme binding activity; predicted to contribute to acetylcholine receptor activity and extracellular ligand-gated ion channel activity; involved in several processes, including acetylcholine receptor signaling pathway, calcium ion transport, and regulation of phosphorus metabolic process; localizes to several cellular components, including the cholinergic synapse, intrinsic component of plasma membrane, and neuron projection; orthologous to several human genes including CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; calcium/calcium-mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BTX; bungarotoxin alpha; C holinergic receptor nicotinic alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha); C holinergic receptor, nicotinic, alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha); cholinergic receptor, nicotinic, alpha 7; cholinergic receptor, nicotinic, alpha 7 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 7; nAChRa7; NARAD; neuronal acetylcholine receptor subunit alpha-7; neuronal nicotinic acetycholine receptor alpha 7; nicotinic receptor alpha 7 subunit
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01123,897,341 - 124,039,263 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01125,029,451 - 125,158,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41117,587,580 - 117,716,267 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11117,665,347 - 117,794,621 (-)NCBI
Celera1108,976,664 - 109,097,764 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Chrna7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2348
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.