Gene: Chrnb2 (cholinergic receptor nicotinic beta 2 subunit) Rattus norvegicus
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Symbol: Chrnb2
Name: cholinergic receptor nicotinic beta 2 subunit
Description: Exhibits acetylcholine binding activity, acetylcholine-gated cation-selective channel activity, and protein heterodimerization activity; predicted to contribute to acetylcholine receptor activity and extracellular ligand-gated ion channel activity; involved in several processes, including acetylcholine receptor signaling pathway, cholinergic synaptic transmission, and positive regulation of dopamine secretion; localizes to the cholinergic synapse, intrinsic component of plasma membrane, and plasma membrane raft; orthologous to human CHRNB2 (cholinergic receptor nicotinic beta 2 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; INTERACTS WITH (S)-anabasine; (S)-nicotine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor nicotinic beta subunit 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2; cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; neuronal acetylcholine receptor non-alpha-1 chain; neuronal acetylcholine receptor subunit beta-2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02189,088,570 - 189,096,785 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02208,511,421 - 208,519,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,961,373 - 181,969,581 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12181,911,478 - 181,919,687 (-)NCBI
Celera2169,123,949 - 169,132,124 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Chrnb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2350
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.