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Gene: Cnp (2',3'-cyclic nucleotide 3' phosphodiesterase) Rattus norvegicus
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Symbol: Cnp
Name: 2',3'-cyclic nucleotide 3' phosphodiesterase
Description: Exhibits 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity and cyclic nucleotide binding activity. Involved in several processes, including aging; regulation of mitochondrial membrane permeability; and response to lipopolysaccharide. Localizes to several cellular components, including mitochondrial membrane; myelin sheath abaxonal region; and myelin sheath adaxonal region. Used to study carotid stenosis. Human ortholog(s) of this gene implicated in multiple sclerosis and schizophrenia. Orthologous to human CNP (2',3'-cyclic nucleotide 3' phosphodiesterase); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 2',3'-cyclic-nucleotide 3'-phosphodiesterase; 2'3'- Cyclic nucleotide 3'-phosphodiesterase; 2,3- Cyclic nucleotide 3-phosphodiesterase; 23- cyclic nucleotide 3-phosphodiesterase; Cnp1; CNPase; CNPF; CNPI; CNPII; cyclic nucleotide phosphodiesterase 1
Orthologs:
Homo sapiens (human) : CNP (2',3'-cyclic nucleotide 3' phosphodiesterase)  HGNC  Alliance
Mus musculus (house mouse) : Cnp (2',3'-cyclic nucleotide 3' phosphodiesterase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cnp (2',3'-cyclic nucleotide 3' phosphodiesterase)
Pan paniscus (bonobo/pygmy chimpanzee) : CNP (2',3'-cyclic nucleotide 3' phosphodiesterase)
Canis lupus familiaris (dog) : CNP (2',3'-cyclic nucleotide 3' phosphodiesterase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cnp (2',3'-cyclic nucleotide 3' phosphodiesterase)
Sus scrofa (pig) : CNP (2',3'-cyclic nucleotide 3' phosphodiesterase)
Chlorocebus sabaeus (African green monkey) : CNP (2',3'-cyclic nucleotide 3' phosphodiesterase)
Heterocephalus glaber (naked mole-rat) : Cnp (2',3'-cyclic nucleotide 3' phosphodiesterase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01088,490,798 - 88,497,357 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,490,798 - 88,497,356 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,284,045 - 88,290,604 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,519,421 - 89,525,978 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11089,533,790 - 89,540,348 (+)NCBI
Celera1084,227,529 - 84,234,088 (+)NCBICelera
Cytogenetic Map10q31NCBI
RH 3.4 Map10859.8RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cnp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2368
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.