Gene: Cps1 (carbamoyl-phosphate synthase 1) Rattus norvegicus
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Symbol: Cps1
Name: carbamoyl-phosphate synthase 1
Description: Exhibits several functions, including anion binding activity, calcium ion binding activity, and carbamoyl-phosphate synthase (ammonia) activity; involved in several processes, including anion homeostasis, cellular response to fibroblast growth factor stimulus, and cellular response to organonitrogen compound; localizes to the mitochondrial inner membrane and protein-containing complex; biomarker of fatty liver disease, hypertension, and obesity; orthologous to human CPS1 (carbamoyl-phosphate synthase 1); PARTICIPATES IN urea cycle pathway; 2-hydroxyglutaric aciduria pathway; AGAT deficiency pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: carbamoyl-phosphate synthase [ammonia], mitochondrial; carbamoyl-phosphate synthetase 1; carbamoyl-phosphate synthetase 1, mitochondrial; carbamoyl-phosphate synthetase I; carbamyl phosphate synthetase I; carbamyl-phosphate synthetase; Carboamyl-phosphate synthetase 1; cps; cps-1; CPSase I
Orthologs:
Homo sapiens (human) : CPS1 (carbamoyl-phosphate synthase 1)  HGNC  Alliance
Mus musculus (house mouse) : Cps1 (carbamoyl-phosphate synthetase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cps1 (carbamoyl-phosphate synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CPS1 (carbamoyl-phosphate synthase 1)
Canis lupus familiaris (dog) : CPS1 (carbamoyl-phosphate synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cps1 (carbamoyl-phosphate synthase 1)
Sus scrofa (pig) : CPS1 (carbamoyl-phosphate synthase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0974,113,437 - 74,236,274 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0973,072,857 - 73,183,868 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4965,907,211 - 66,017,942 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1966,054,192 - 66,164,924 (+)NCBI
Celera966,092,717 - 66,214,118 (+)NCBICelera
Cytogenetic Map9q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cps1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2395
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.