Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Crhbp (corticotropin releasing hormone binding protein) Rattus norvegicus
Symbol: Crhbp
Name: corticotropin releasing hormone binding protein
Description: Exhibits corticotropin-releasing hormone binding activity. Involved in several processes, including cellular response to estrogen stimulus; cellular response to immobilization stress; and cellular response to organic cyclic compound. Localizes to several cellular components, including axon; cytoplasmic vesicle; and perikaryon. Biomarker of mental depression; obesity; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in mental depression. Orthologous to human CRHBP (corticotropin releasing hormone binding protein); PARTICIPATES IN corticotropin-releasing hormone signaling pathway; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: corticotropin releasing factor binding protein; corticotropin-releasing factor-binding protein; corticotropin-releasing hormone-binding protein; CRF-binding protein; CRF-BP; Crfbp; CRH-BP
Homo sapiens (human) : CRHBP (corticotropin releasing hormone binding protein)  HGNC  Alliance
Mus musculus (house mouse) : Crhbp (corticotropin releasing hormone binding protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crhbp (corticotropin releasing hormone binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : CRHBP (corticotropin releasing hormone binding protein)
Canis lupus familiaris (dog) : CRHBP (corticotropin releasing hormone binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crhbp (corticotropin releasing hormone binding protein)
Sus scrofa (pig) : CRHBP (corticotropin releasing hormone binding protein)
Chlorocebus sabaeus (African green monkey) : CRHBP (corticotropin releasing hormone binding protein)
Heterocephalus glaber (naked mole-rat) : Crhbp (corticotropin releasing hormone binding protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0225,141,471 - 25,153,334 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl225,141,471 - 25,153,334 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0244,299,507 - 44,311,225 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4225,801,371 - 25,813,457 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1225,721,739 - 25,733,799 (-)NCBI
Celera222,758,077 - 22,770,045 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Crhbp
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2403
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.