Gene: Crp (C-reactive protein) Rattus norvegicus
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Symbol: Crp
Name: C-reactive protein
Description: Exhibits cholesterol binding activity, low-density lipoprotein particle binding activity, and protein homodimerization activity; involved in several processes, including acute-phase response, aging, and regulation of reactive oxygen species metabolic process; localizes to the extracellular space, filopodium, and growth cone; used to study rheumatoid arthritis; biomarker of several diseases, including acute kidney failure, artery disease (multiple), colon cancer, familial hyperlipidemia, and iron deficiency anemia; orthologous to human CRP (C-reactive protein); PARTICIPATES IN classical complement pathway; interleukin-6 signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-lipoic acid; (R)-rosmarinic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Aa1249; Ab1-341; Ab2-196; Ac1-114; Ac1262; Ac2-069; Ba2-693; C-reactive protein member of the pentraxin family; C-reactive protein, member of the pentraxin family; C-reactive protein, pentraxin-related; C-reactive protein, petaxin related
Orthologs:
Homo sapiens (human) : CRP (C-reactive protein)  HGNC  Alliance
Mus musculus (house mouse) : Crp (C-reactive protein, pentraxin-related)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CRP (C-reactive protein)
Canis lupus familiaris (dog) : CRP (C-reactive protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crp (C-reactive protein)
Sus scrofa (pig) : CRP (C-reactive protein, pentraxin-related)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01391,080,448 - 91,081,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01395,599,418 - 95,600,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,702,243 - 88,703,153 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11388,891,058 - 88,892,928 (+)NCBI
Celera1384,770,843 - 84,771,753 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Crp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2411
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.