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Gene: Csf3 (colony stimulating factor 3) Rattus norvegicus
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Symbol: Csf3
Name: colony stimulating factor 3
Description: Exhibits growth factor activity. Involved in several processes, including cellular response to lipopolysaccharide; negative regulation of neuron death; and response to ethanol. Localizes to the extracellular space. Biomarker of cystitis; lung disease; and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in several diseases, including allergic cutaneous vasculitis; artery disease (multiple); ischemia (multiple); leukemia (multiple); and lung disease (multiple). Orthologous to human CSF3 (colony stimulating factor 3); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; malaria pathway; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 2-amino-2-deoxy-D-glucopyranose; aldehydo-D-glucosamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: colony stimulating factor 3 (granulocyte); Gcsf; granulocyte colony-stimulating factor
Orthologs:
Homo sapiens (human) : CSF3 (colony stimulating factor 3)  HGNC  Alliance
Mus musculus (house mouse) : Csf3 (colony stimulating factor 3 (granulocyte))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf3 (colony stimulating factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF3 (colony stimulating factor 3)
Canis lupus familiaris (dog) : CSF3 (colony stimulating factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf3 (colony stimulating factor 3)
Sus scrofa (pig) : CSF3 (colony stimulating factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01086,616,785 - 86,619,160 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01086,413,088 - 86,415,478 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,473,990 - 87,476,365 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11087,488,359 - 87,490,732 (+)NCBI
Celera1082,409,331 - 82,411,709 (+)NCBICelera
Cytogenetic Map10q31NCBI
RH 3.4 Map10850.39RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Csf3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2426
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.