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Gene: Ctbp1 (C-terminal binding protein 1) Rattus norvegicus
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Symbol: Ctbp1
Name: C-terminal binding protein 1
Description: Exhibits NAD binding activity; PDZ domain binding activity; and protein homodimerization activity. Involved in presynapse to nucleus signaling pathway. Localizes to several cellular components, including the glutamatergic synapse; nucleus; and presynapse. Orthologous to human CTBP1 (C-terminal binding protein 1); PARTICIPATES IN Notch signaling pathway; chronic myeloid leukemia pathway; Wnt signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 50 kDa BFA-dependent ADP-ribosylation substrate; 50-kDa BFA-induced ADP-ribosylated substrate; 50-kDaBFA-inducedADP-ribosylatedsubstrate; BARS; BARS-50; brefeldin A-ADP-riboslyated substrate; C-terminal-binding protein 1; C-terminal-binding protein 3; C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate; ctBP3; CtBP3/BARS; MGC93318
Orthologs:
Homo sapiens (human) : CTBP1 (C-terminal binding protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Ctbp1 (C-terminal binding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctbp1 (C-terminal binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CTBP1 (C-terminal binding protein 1)
Canis lupus familiaris (dog) : CTBP1 (C-terminal binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctbp1 (C-terminal binding protein 1)
Sus scrofa (pig) : CTBP1 (C-terminal binding protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01482,762,109 - 82,789,350 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01483,447,911 - 83,475,152 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41483,022,824 - 83,050,335 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11483,025,214 - 83,052,726 (-)NCBI
Celera1476,376,169 - 76,398,029 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ctbp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2441
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.