Gene: Ctsc (cathepsin C) Rattus norvegicus
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Symbol: Ctsc
Name: cathepsin C
Description: Exhibits several functions, including chaperone binding activity, chloride ion binding activity, and identical protein binding activity; involved in several processes, including aging, positive regulation of proteolysis involved in cellular protein catabolic process, and proteolysis; localizes to the Golgi apparatus, endoplasmic reticulum, and lysosome; biomarker of brain ischemia, hypertension, and obesity; orthologous to human CTSC (cathepsin C); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CATC; Cathepsin C (dipeptidyl peptidase I); cathepsin J; dipeptidyl peptidase 1; dipeptidyl peptidase I; dipeptidyl transferase; dipeptidyl-peptidase 1; dipeptidyl-peptidase I; DPP-I; DPPI
Orthologs:
Homo sapiens (human) : CTSC (cathepsin C)  HGNC  Alliance
Mus musculus (house mouse) : Ctsc (cathepsin C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctsc (cathepsin C)
Pan paniscus (bonobo/pygmy chimpanzee) : CTSC (cathepsin C)
Canis lupus familiaris (dog) : CTSC (cathepsin C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctsc (cathepsin C)
Sus scrofa (pig) : CTSC (cathepsin C)
more info ...
Is Marker For: Strains:   FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01151,918,514 - 151,949,979 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01158,231,534 - 158,263,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41144,629,802 - 144,661,183 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11144,708,207 - 144,739,589 (+)NCBI
Celera1140,327,884 - 140,359,275 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ctsc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2445
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.