Gene: Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2) Rattus norvegicus
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Description: Exhibits oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; involved in several processes, including cellular response to copper ion, response to drug, and response to estradiol; localizes to the intracellular membrane-bounded organelle; biomarker of mental depression; orthologous to human CYP1A2 (cytochrome P450 family 1 subfamily A member 2); PARTICIPATES IN caffeine pharmacokinetics pathway; clomipramine pharmacokinetics pathway; clopidogrel pharmacodynamics pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-artemisinin; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cholesterol 25-hydroxylase; CYPD45; CYPIA2; cytochrome P-448; cytochrome P-450d; cytochrome P450 1A2; Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450, 1a2; Cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450-D; P-448; P-450d; P450-D; RATCYPD45
Homo sapiens (human) : CYP1A2 (cytochrome P450 family 1 subfamily A member 2)  HGNC  Alliance
Mus musculus (house mouse) : Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102010322 (cytochrome P450 1A2)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100975837 (cytochrome P450 1A2)
Canis lupus familiaris (dog) : CYP1A2 (cytochrome P450 family 1 subfamily A member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969421 (cytochrome P450 1A2)
Sus scrofa (pig) : CYP1A2 (cytochrome P450, family 1, subfamily A, polypeptide 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0862,451,360 - 62,458,244 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,228,271 - 62,235,203 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,439,062 - 61,447,861 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1861,458,143 - 61,464,586 (-)NCBI
Celera857,541,217 - 57,547,956 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations