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Gene: Cyp1b1 (cytochrome P450, family 1, subfamily b, polypeptide 1) Rattus norvegicus
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Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Description: Exhibits monooxygenase activity. Involved in several processes, including positive regulation of cellular metabolic process; response to gonadotropin; and response to steroid hormone. Localizes to nucleus. Biomarker of breast adenocarcinoma and esophagus squamous cell carcinoma. Human ortholog(s) of this gene implicated in Peters anomaly; anterior segment dysgenesis 6; breast cancer; glaucoma (multiple); and lung squamous cell carcinoma. Orthologous to human CYP1B1 (cytochrome P450 family 1 subfamily B member 1); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; steroid hormone biosynthetic pathway; tryptophan metabolic pathway; INTERACTS WITH 1,2,3,4,6,7,8-Heptachlorodibenzodioxin; 1,2,3,4,6,7,8-Heptachlorodibenzofuran; 1,2,3,4,7,8-Hexachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CYPIB1; cytochrome P450 1b1; cytochrome P450, subfamily 1B, polypeptide 1; cytochrome P450RAP; hydroperoxy icosatetraenoate dehydratase; P450RAP
Orthologs:
Homo sapiens (human) : CYP1B1 (cytochrome P450 family 1 subfamily B member 1)  HGNC  Alliance
Mus musculus (house mouse) : Cyp1b1 (cytochrome P450, family 1, subfamily b, polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102009223 (cytochrome P450 1B1)
Pan paniscus (bonobo/pygmy chimpanzee) : CYP1B1 (cytochrome P450 family 1 subfamily B member 1)
Canis lupus familiaris (dog) : CYP1B1 (cytochrome P450 family 1 subfamily B member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101970101 (cytochrome P450 1B1)
Sus scrofa (pig) : LOC100625479 (cytochrome P450 1B1)
Chlorocebus sabaeus (African green monkey) : CYP1B1 (cytochrome P450 family 1 subfamily B member 1)
Heterocephalus glaber (naked mole-rat) : LOC101701066 (cytochrome P450 1B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.062,308,179 - 2,316,739 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl62,307,808 - 2,316,722 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.062,294,952 - 2,300,644 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.462,548,224 - 2,553,767 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.162,545,648 - 2,553,767 (-)NCBI
Celera615,009,941 - 15,015,671 (+)NCBICelera
Cytogenetic Map6q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)