Gene: Cyp2b1 (cytochrome P450, family 2, subfamily b, polypeptide 1) Rattus norvegicus
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Symbol: Cyp2b1
Name: cytochrome P450, family 2, subfamily b, polypeptide 1
Description: Exhibits Hsp70 protein binding activity, Hsp90 protein binding activity, and steroid hydroxylase activity; involved in several processes, including drug metabolic process, response to calcium ion, and response to drug; localizes to the mitochondrial inner membrane; biomarker of mental depression and obesity; orthologous to human CYP2B6 (cytochrome P450 family 2 subfamily B member 6); PARTICIPATES IN arachidonic acid metabolic pathway; phase I biotransformation pathway via cytochrome P450; retinol metabolic pathway; INTERACTS WITH (+)-artemisinin; (-)-cotinine; (2-trans,6-trans)-farnesol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cyp2b-1; Cypbe; CYPIIB1; cytochrome P450 2B1; Cytochrome P450, subfamily IIB (phenobarbital-inducible) (b, e); cytochrome P450-B; cytochrome P450-LM2; cytochrome P450-PB1; cytochrome P450-PB2; cytochrome P450b; MGC188065; P450-B; P450-LM2; P450-PB1 and P450-PB2; P450b
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0799,142,431 - 99,183,540 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0799,752,108 - 99,777,546 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4181,266,828 - 81,290,471 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1181,341,201 - 81,344,952 (+)NCBI
Celera175,950,659 - 75,974,302 (+)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp2b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2466
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.