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Gene: Cyp2d3 (cytochrome P450, family 2, subfamily d, polypeptide 3) Rattus norvegicus
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Symbol: Cyp2d3
Name: cytochrome P450, family 2, subfamily d, polypeptide 3
Description: Exhibits monooxygenase activity. Involved in liver development. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in acute myeloid leukemia; asthma; autoimmune hepatitis; precursor lymphoblastic lymphoma/leukemia; and rhinitis. Orthologous to human CYP2D6 (cytochrome P450 family 2 subfamily D member 6); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cyp2d13; Cyp2d6; CYPIID3; cytochrome P450 2D3; cytochrome P450, family 2, subfamily d, polypeptide 13; cytochrome P450, family 2, subfamily d, polypeptide 6; Cytochrome P450, subfamily IID3; cytochrome P450-DB3; debrisoquine 4-hydroxylase; MGC108561; P450-DB3
Orthologs:
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07123,634,400 - 123,638,757 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,625,590 - 123,638,765 (-)Ensembl
Rnor_5.07123,619,362 - 123,623,719 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,778,783 - 120,783,140 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,813,012 - 120,817,370 (-)NCBI
Celera7110,232,895 - 110,237,252 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp2d3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2472
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.