Gene: Dbh (dopamine beta-hydroxylase) Rattus norvegicus
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Symbol: Dbh
Name: dopamine beta-hydroxylase
Description: Exhibits copper ion binding activity and dopamine beta-monooxygenase activity; involved in several processes, including bone development, cellular response to manganese ion, and cellular response to nicotine; localizes to several cellular components, including the apical part of cell, cytoplasmic vesicle, and neuron projection; biomarker of brain ischemia, hypertension, mental depression, and portal hypertension; orthologous to human DBH (dopamine beta-hydroxylase); PARTICIPATES IN alkaptonuria pathway; aromatic L-amino acid decarboxylase deficiency pathway; catecholamine biosynthetic pathway; INTERACTS WITH 2,4-D; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dopamine beta hydroxylase; Dopamine beta hydroxylase (dopamine beta-monooxygenase); dopamine beta-hydroxylase (dopamine beta-monooxygenase); dopamine beta-monooxygenase; DOPBHY
Orthologs:
Homo sapiens (human) : DBH (dopamine beta-hydroxylase)  HGNC  Alliance
Mus musculus (house mouse) : Dbh (dopamine beta hydroxylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dbh (dopamine beta-hydroxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : DBH (dopamine beta-hydroxylase)
Canis lupus familiaris (dog) : DBH (dopamine beta-hydroxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dbh (dopamine beta-hydroxylase)
Sus scrofa (pig) : DBH (dopamine beta-hydroxylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.035,709,236 - 5,731,895 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0311,073,477 - 11,095,363 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.436,052,706 - 6,069,826 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.136,053,005 - 6,070,129 (+)NCBI
Celera35,285,082 - 5,302,054 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dbh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2489
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.