Gene: Drd3 (dopamine receptor D3) Rattus norvegicus
Symbol: Drd3
Name: dopamine receptor D3
Description: Exhibits several functions, including D1 dopamine receptor binding activity, dopamine binding activity, and dopamine neurotransmitter receptor activity, coupled via Gi/Go; involved in several processes, including G protein-coupled receptor internalization, acid secretion, and regulation of cellular biosynthetic process; localizes to several cellular components, including the GABA-ergic synapse, apical part of cell, and cell projection; used to study amnestic disorder, essential tremor, and hypertension; biomarker of heroin dependence and visual epilepsy; orthologous to human DRD3 (dopamine receptor D3); PARTICIPATES IN dopamine signaling pathway; dopamine signaling pathway via D2 family of receptors; G protein mediated signaling pathway via Galphai family; INTERACTS WITH (R,R)-tramadol; (RS)-amphetamine; (S)-colchicine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D(3) dopamine receptor; D3 receptor; dopamine D3 receptor; dopamine D3 receptor isoform; dopaminergic receptor D3
Homo sapiens (human) : DRD3 (dopamine receptor D3)  HGNC  Alliance
Mus musculus (house mouse) : Drd3 (dopamine receptor D3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Drd3 (dopamine receptor D3)
Pan paniscus (bonobo/pygmy chimpanzee) : DRD3 (dopamine receptor D3)
Canis lupus familiaris (dog) : DRD3 (dopamine receptor D3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Drd3 (dopamine receptor D3)
Sus scrofa (pig) : DRD3 (dopamine receptor D3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01161,819,102 - 61,883,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01160,955,136 - 61,016,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41158,446,901 - 58,520,589 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11158,504,489 - 58,578,178 (-)NCBI
Celera1156,432,639 - 56,484,538 (-)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Drd3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2521
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.