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Gene: Drd5 (dopamine receptor D5) Rattus norvegicus
Symbol: Drd5
Name: dopamine receptor D5
Description: Exhibits G-protein alpha-subunit binding activity; dopamine neurotransmitter receptor activity, coupled via Gs; and drug binding activity. Involved in several processes, including adenylate cyclase-activating dopamine receptor signaling pathway; regulation of long-term neuronal synaptic plasticity; and visual learning. Localizes to several cellular components, including brush border membrane; glutamatergic synapse; and integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and blepharospasm. Orthologous to human DRD5 (dopamine receptor D5); PARTICIPATES IN dopamine signaling pathway; long term depression; long term potentiation; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: d(1B) dopamine receptor; d(5) dopamine receptor; D1B; dopamine D5 receptor; dopamine receptor 5
Homo sapiens (human) : DRD5 (dopamine receptor D5)  HGNC  Alliance
Mus musculus (house mouse) : Drd5 (dopamine receptor D5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Drd5 (dopamine receptor D5)
Pan paniscus (bonobo/pygmy chimpanzee) : DRD5 (dopamine receptor D5)
Canis lupus familiaris (dog) : DRD5 (dopamine receptor D5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Drd5 (dopamine receptor D5)
Sus scrofa (pig) : DRD5 (dopamine receptor D5)
Chlorocebus sabaeus (African green monkey) : DRD5 (dopamine receptor D5)
Heterocephalus glaber (naked mole-rat) : Drd5 (dopamine receptor D5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01477,220,579 - 77,222,006 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1477,220,579 - 77,222,006 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01477,202,167 - 77,203,594 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41477,768,060 - 77,769,487 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11477,770,450 - 77,771,878 (-)NCBI
Celera1471,440,495 - 71,441,922 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Drd5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2523
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.