Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Edn2 (endothelin 2) Rattus norvegicus
Analyze
Symbol: Edn2
Name: endothelin 2
Description: Predicted to have endothelin B receptor binding activity and hormone activity. Involved in several processes, including ovarian follicle rupture; protein kinase C-activating G protein-coupled receptor signaling pathway; and regulation of hormone secretion. Localizes to the extracellular space. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human EDN2 (endothelin 2); PARTICIPATES IN endothelin signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; BQ 123.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Endothelin isopeptide 2; endothelin-2; ET-2; Et2; PPET2; preproendothelin-2; RNEDN2S01; vasoactive intestinal contractor; VIC
Orthologs:
Homo sapiens (human) : EDN2 (endothelin 2)  HGNC  Alliance
Mus musculus (house mouse) : Edn2 (endothelin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Edn2 (endothelin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EDN2 (endothelin 2)
Canis lupus familiaris (dog) : EDN2 (endothelin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Edn2 (endothelin 2)
Sus scrofa (pig) : EDN2 (endothelin 2)
more info ...
Is Marker For: QTLs:   Bp7  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05139,098,472 - 139,106,396 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05142,891,221 - 142,896,115 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45140,742,686 - 140,747,580 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15140,747,827 - 140,753,399 (+)NCBI
Celera5132,309,615 - 132,315,113 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Edn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2533
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.