Gene: Egf (epidermal growth factor) Rattus norvegicus
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Symbol: Egf
Name: epidermal growth factor
Description: Exhibits epidermal growth factor receptor binding activity; involved in several processes, including epidermal growth factor receptor signaling pathway, kidney development, and positive regulation of cellular metabolic process; localizes to the extracellular space; used to study perinatal necrotizing enterocolitis; biomarker of acute kidney failure; orthologous to human EGF (epidermal growth factor); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; altered epidermal growth factor/neuregulin signaling pathway; ceramide signaling pathway; INTERACTS WITH (R)-noradrenaline; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: pro-epidermal growth factor
Orthologs:
Homo sapiens (human) : EGF (epidermal growth factor)  HGNC  Alliance
Mus musculus (house mouse) : Egf (epidermal growth factor)  MGI  Alliance
Sus scrofa (pig) : EGF (epidermal growth factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0268,820,616 - 68,895,537 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0274,746,752 - 74,783,449 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0288,549,746 - 88,621,570 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02253,481,574 - 253,482,579 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42227,103,900 - 227,195,062 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12227,090,579 - 227,181,742 (-)NCBI
Celera2210,511,076 - 210,588,041 (-)NCBICelera
Cytogenetic Map2q21NCBI
RH 3.4 Map21556.7RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Egf
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2542
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.