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Gene: Eno1 (enolase 1) Rattus norvegicus
Symbol: Eno1
Name: enolase 1
Description: Exhibits several functions, including enzyme binding activity; phosphopyruvate hydratase activity; and protein dimerization activity. Involved in cellular response to hypoxia; phosphorylation; and protein heterotetramerization. Localizes to several cellular components, including the cytoplasm; growth cone; and membrane raft. Biomarker of hypertension. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human ENO1 (enolase 1); PARTICIPATES IN gluconeogenesis pathway; Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; INTERACTS WITH (RS)-amphetamine; 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2-phospho-D-glycerate hydro-lyase; alpha enolase; alpha-enolase; enolase 1, (alpha); enolase 1, alpha; enolase 1, alpha non-neuron; NNE; non-neural enolase
Homo sapiens (human) : ENO1 (enolase 1)  HGNC  Alliance
Mus musculus (house mouse) : Eno1 (enolase 1, alpha non-neuron)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eno1 (enolase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ENO1 (enolase 1)
Canis lupus familiaris (dog) : ENO1 (enolase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eno1 (enolase 1)
Sus scrofa (pig) : ENO1 (enolase 1)
more info ...
Related Pseudogenes: Eno1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05167,288,223 - 167,299,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05170,915,874 - 170,927,267 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45167,394,131 - 167,405,516 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15167,404,823 - 167,415,701 (+)NCBI
Celera5158,976,607 - 158,987,992 (+)NCBICelera
Cytogenetic Map5q36NCBI
RH 3.4 Map51122.0RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Eno1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2553
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.