Gene: F3 (coagulation factor III, tissue factor) Rattus norvegicus
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Symbol: F3
Name: coagulation factor III, tissue factor
Description: Exhibits protease binding activity; predicted to contribute to serine-type endopeptidase activity; involved in several processes, including aging, cellular response to hydrogen peroxide, and cellular response to low-density lipoprotein particle stimulus; localizes to the cell surface, cytoplasm, and extracellular space; biomarker of disseminated intravascular coagulation, hypertension, and myocardial infarction; orthologous to human F3 (coagulation factor III, tissue factor); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; INTERACTS WITH (RS)-amphetamine; (S)-colchicine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: coagulation factor 3; coagulation factor III; Coagulation factor III (thromboplastin tissue factor); coagulation factor III (thromboplastin, tissue factor); MGC93621; TF; tissue factor
Orthologs:
Homo sapiens (human) : F3 (coagulation factor III, tissue factor)  HGNC  Alliance
Mus musculus (house mouse) : F3 (coagulation factor III)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F3 (coagulation factor III, tissue factor)
Pan paniscus (bonobo/pygmy chimpanzee) : F3 (coagulation factor III, tissue factor)
Canis lupus familiaris (dog) : F3 (coagulation factor III, tissue factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F3 (coagulation factor III, tissue factor)
Sus scrofa (pig) : F3 (coagulation factor III, tissue factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02225,310,686 - 225,322,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02243,348,430 - 243,360,439 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42218,371,050 - 218,382,645 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12218,334,111 - 218,345,706 (+)NCBI
Celera2202,257,415 - 202,269,039 (+)NCBICelera
Cytogenetic Map2q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on F3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 2587
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.